Figure 6.

PPARγ agonists ameliorate memory impairment in db/db mice. In the MWM task, day 0 indicates performance on the first trial, and subsequent points represent average of all daily trials. (A) No differences were found in the escape latency among all groups during the 2‐day visible platform test. (B) Changes in escape latency to reach the hidden platform during the 3‐day acquisition trials, (C) representative swim paths during the spatial probe test, (D) the percentage of total time in the target quadrant, (E) the number of target crossings during the probe trial test, (F) the number of correct choices on days 1–2 and (G) the latency to enter the shock‐free compartment on day 2 in the Y‐maze test. Values shown are expressed as mean ± SEM; n = 8–10. *P < 0.05, **P < 0.01 versus db/db + Veh group.