Skip to main content
. 2016 Feb 22;173(6):1058–1069. doi: 10.1111/bph.13418

Figure 1.

Figure 1

Blockade of α1‐adrenoceptor signalling impaired cancellous bone mass in mice. (A–D) μCT‐based bone densitometry of the distal region of the femur in 12‐week‐old male mice administered saline (white bar) or prazosin at 1, 3, 10 and 30 μg·kg−1 body wt. day−1 for 2 weeks. (A) BV/TV. (B) Tb.N. (C) Tb.Th. (D) Tb.Sp. n = 8 or 17 mice per group. Similar results were obtained in three independent experiments. Values are expressed as means ± SEM. * P < 0.05 significantly different from control mice.