Table 1.
Bioinformatics analysis of the potential phospho sites on BMI1 protein sequence
| Scorea | Sequencea | Siteb | Predicted kinase |
|---|---|---|---|
| 0.994 | KFLRSKMDI | S181 | PKB/ATM/Aurora/MAPK |
| 0.993 | LESDSGSDK | S253 | ATM/PLK1/CK2 |
| 0.991 | PRKSSVNGS | S316 | PKB/ATM/Aurora/IKK/CAMK/PLK1 |
| 0.987 | SDSGSDKAN | S255 | ATM/Aurora/CDK |
| 0.987 | RPRKSSVNG | S315 | ATM/Aurora/IKK/CAMK |
| 0.984 | DKANSPAGG | S260 | ATM/Aurora/PLK1/MAPK/CK1 |
| 0.955 | TPVQSPHPQ | S281 | ATM/Aurora/MAPK/CDK/CK1 |
| 0.951 | AANGSNEDR | S110 | ATM/CK2 |
| 0.918 | YLETSKYCP | S50 | ATM |
The data derived from NetPhos2.0 server and KinasePhos 2 are indicated by a and b respectively