Table 4.
Sedentary‐placebo | Sedentary‐ESA | Training‐placebo | Training‐ESA | |||||
---|---|---|---|---|---|---|---|---|
Pre | Post | Pre | Post | Pre | Post | Pre | Post | |
Myonuclei/fibre | ||||||||
Fibre type I | 2.03 ± 0.19 | 1.91 ± 0.16 | 1.685 ± 0.201 | 1.42 ± 0.18 | 1.72 ± 0.12 | 1.55 ± 0.12 | 2.01 ± 0.27 | 1.44 ± 0.12 |
Fibre type II | 2.21 ± 0.24 | 2.06 ± 0.17 | 2.03 ± 0.182 | 1.91 ± 0.29 | 1.84 ± 0.25 | 1.965 ± 0.25 | 2.18 ± 0.29 | 2.02 ± 0.27 |
Hybrid fibres | 2a | 2.50 (0.0–3.0) | 2.75 (0.0–3.0) | 1.05 (0.0––4.0) | NA | 0 (0.0–2.0) | 0.67 (0.0–1.3) | 2.38 (0.0–2.7) |
SC/100 myonuclei | ||||||||
Fibre type I | 2.5 ± 1.0 | 3.0 ± 0.7 | 5.0 ± 0.8 | 5.5 ± 1.7 | 3.7 ± 0.8 | 2.9 ± 0.4 | 2.6 ± 0.7 | 5.3 ± 1.1 |
Fibre type II | 2.7 ± 1.1 | 2.3 ± 0.7 | 2.9 ± 0.5 | 3.2 ± 0.5 | 2.0 ± 0.3 | 3.1 ± 0.6* | 1.2 ± 0.5 | 3.2 ± 0.6* |
Hybrid fibres | 6.8a | 0 (0.0–2.2) | 1.3 (0.0–4.6) | 8.3 (0.0–18.2) | NA | NA | 2.7 (0.0–5.4) | 0 (0.0–4.6) |
Myonuclei per fibre and satellite cells per myonclei in type I, type II and hybrid fibres pre and post 10 weeks of sedentary‐placebo, sedentary‐ESA, training‐placebo or training‐ESA treatment. Data are the mean ± SE for type I and type II fibres and median (range) for hybrid fibres. Significant change from pre is indicated by * (P < 0.05). a n = 1 included in analysis. NA, not available.