Scheme 1.
Reagents and conditions. (a) Boc2O, DMAP, CH2Cl2; (b) ClSn(CH3)3, LDA/THF; (c) Br-Ar-CN, Pd(PPh3)4, Dioxane (d) 1-LiN(TMS)2/THF,2-HCl gas/EtOH.
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