Table.
Analysis of relationship between GB119 activation and presence of skin cancer in human skin samples
Measure | Group Examined | Regions of Interest (ROIs) | Sensitivity/Specificity | 95% Confidence Interval (2-sided) |
---|---|---|---|---|
Sensitivity | All patients | 90 | 0.989 (89/90) | 0.940–1.000 |
BCC only | 56 | 1.000 (56/56) | 0.936–1.000 | |
SCC only | 34 | 0.971 (33/34) | 0.847–1.000 | |
Specificity | All patients | 47 | 0.894 (42/47) | 0.769–0.965 |
BCC only | 23 | 0.870 (20/23) | 0.664–0.972 | |
SCC only | 24 | 0.917 (22/24) | 0.730–0.990 |
For these studies 55 patient samples were assessed. These samples included 35 BCC (N=8, MN=10, I=4, and S=8, M=5) and 20 SCC (WD=15, MD=3, PD=0, M=2) specimens. BCC – basal cell carcinoma; N – nodular, MN – micro-nodular, S – superficial, and I – infiltrative form of BCC; SCC – squamous cell carcinoma; WD – well differentiated, MD – mildly differentiated, and PD – poorly differentiated of SCC. M=mixed pathology for either BCC or SCC.