Table 4. Genetic risk score for the four PC risk associated variants from the meta-analysisa.
Number of Risk Alleles of Controls | Number of Cases | Percent of Cases | Number of Controls | Percent of Controls | ORb | 95% CIc | P |
---|---|---|---|---|---|---|---|
0 | 5,087 | 92.98 | 3,928 | 95.60 | 1.00 | Reference | |
1 | 367 | 6.71 | 178 | 4.33 | 1.58 | 1.31 – 1.91 | 1.0 × 10−7 |
2 or 3 | 17 | 0.31 | 3 | 0.07 | 4.25 | 1.20 – 14.97 | 0.024 |
≥1 | 384 | 7.02 | 181 | 4.40 | 1.63 | 1.36 – 1.95 | 1.4 × 10−7 |
Only cases and controls with genotypes available for all four variants are included.
Meta-analysis of age adjusted data.
95% Confidence Interval.