Table 2.
Factors Associated with the Mortality over the 5-years After AMI
| HR (95% CI) | Chi-Square Value | p-value | |
|---|---|---|---|
| Admission creatinine (+50%) | 1.27 (1.18–1.36) | 45.3 | <0.001 |
| Not currently working | 1.95 (1.47–2.58) | 22.0 | <0.001 |
| Age (+10 years) | 1.29 (1.16–1.44) | 20.8 | <0.001 |
| Admission hemoglobin (+1 mg/dL) | 0.90 (0.85–0.94) | 16.5 | <0.001 |
| Left ventricular systolic dysfunction | 1.50 (1.20–1.86) | 13.2 | <0.001 |
| Chronic heart failure | 1.51 (1.19–1.92) | 11.6 | 0.001 |
| Active during leisure time | 1.83 (1.29–2.59) | 11.5 | 0.001 |
| Chronic lung disease | 1.55 (1.17–2.05) | 9.6 | 0.002 |
| In-hospital revascularization | 0.72 (0.59–0.89) | 9.0 | 0.003 |
| Body mass index (+5 kg/m2) | 0.90 (0.83–0.97) | 7.9 | 0.005 |
| Currently on insulin | 1.34 (1.08–1.68) | 6.9 | 0.009 |
| Fasting glucose (+100 mg/dL) | 1.19 (1.04–1.35) | 6.4 | 0.012 |
| Prior myocardial infarction | 1.28 (1.03–1.60) | 4.9 | 0.027 |
|
| |||
| SAQ Angina Frequency (−10 points) | 0.95 (0.91–1.00) | 4.2 | 0.041 |
| Prior bypass graft surgery | 1.24 (0.98–1.57) | 3.3 | 0.067 |
| Peak troponin (+100 ng/mL) | 1.17 (0.99–1.39) | 3.3 | 0.068 |
| Prior stroke/TIA | 1.23 (0.94–1.61) | 2.2 | 0.134 |
| ST-elevation myocardial infarction | 0.83 (0.64–1.09) | 1.8 | 0.181 |
| Depression (PHQ-9 ≥ 10) | 1.19 (0.92–1.53) | 1.7 | 0.187 |
| Health insurance | 1.19 (0.88–1.61) | 1.2 | 0.264 |
| Avoids care due to cost | 1.13 (0.89–1.44) | 1.1 | 0.305 |
| Peripheral vascular disease | 1.13 (0.84–1.53) | 0.7 | 0.418 |
| Non-Caucasian race | 0.92 (0.74–1.14) | 0.6 | 0.440 |
| Current smoker | 1.10 (0.86–1.42) | 0.6 | 0.447 |
| Female | 0.93 (0.75–1.16) | 0.4 | 0.537 |
| High emotional stress (PSS-4 ≥ 9) | 1.11 (0.82–1.50) | 0.4 | 0.509 |
| Prior coronary stenting | 1.04 (0.82–1.31) | 0.1 | 0.746 |
| Atrial fibrillation/flutter | 1.01 (0.73–1.41) | 0.0 | 0.935 |
| Hemoglobin A1c (+1%) | 1.00 (0.94–1.07) | 0.0 | 0.990 |
| SAQ Quality of Life (−10 points) | 1.00 (0.95–1.04) | 0.0 | 0.859 |
Variables above the line comprise the reduced model (Supplemental Table 4)
Full model (apparent): c-index=0.80, calibration slope=1.00
Full model (bootstrap validated): c-index=0.79, calibration slope=0.92
Reduced model (apparent): c-index=0.79, calibration slope=1.00
Reduced model (bootstrap validated): c-index=0.78, calibration slope=0.92
Reduced model (externally validated): c-index=0.78, calibration slope=0.92