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. 2016 Sep 13;7(41):66398–66415. doi: 10.18632/oncotarget.12012

Figure 7. Smyd2 is a direct Myc target.

Figure 7

Quantitative RT-PCR analysis of the Smyd2 mRNA in splenic B-cells of Eμ-myc and non-transgenic mice A. and upon hydroxy-tamoxifen (OHT)-induced MycER activation in mouse embryo fibroblasts (MEF-MycER) B. Nucleolin and Cyclin B1 (CycB1) are known Myc targets, used as positive controls. Averages values and error bars are from three biological replicates. Tbp was used as the house-keeping gene to calculate relative mRNA levels. C. Myc ChIP-Seq profiles at the Smyd2 locus in 3T9 fibroblasts and B-cell samples, as indicated [8, 9].