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. 2016 Sep 13;7(41):66416–66428. doi: 10.18632/oncotarget.12013

Figure 1. Effect of aging and gonadectomy on autophagosome number in OST.

Figure 1

LC3-II level, which reflects autophagosome number, was determined by Western blot in cortical bone. LC3-II to β-actin relative levels are expressed as means ± standard errors. A. Comparison of LC3-II expression in cortical bone from 2 month-old (n = 3) and 24 month-old (n = 3) male mice. B. Comparison of LC3-II expression in cortical bone from 2 month-old (n = 3) and 24 month-old (n = 3) female mice. C. Comparison of LC3-II expression in cortical bone from sham (n = 3) and OCX (n = 3) male mice. D. Comparison of LC3-II expression in cortical bone from sham (n = 2) and OVX (n = 4) female mice. * = P < 0.05.