Figure 5. Effect of autophagy deficiency in OB on bone phenotype induced by aging and ovariectomy.
Eighteen month-old female Atg5Col1A-Cre+ (mutant, M) mice and their control littermates (control, C) were ovariectomized (C OVX, n = 6; M OVX, n = 4) or sham-operated (C Sham, n = 12; M Sham, n = 8). A.-C. The percentage of bone volume per total volume (BV/TV), the trabecular thickness (Tb.Th) and the trabecular number (Tb.N) in each group are presented. The mean is indicated in each histogram. * = P < 0.05.