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. 2016 Sep 12;7(41):66468–66479. doi: 10.18632/oncotarget.11979

Figure 4. CEACAM1 induction is mediated by RIG-I and IRF3.

Figure 4

a.-b. qRT-PCR quantification of RIG-I (a) and IRF3 (b) expression in A549 cells that underwent IRF3 and RIG-I targeted shRNA knockdowns compared with the same cells transduced with scrambled shRNA (Scrambled set as 1). c. The scrambled A549 cells and the specific shRNA knockdown cells from (a) and (b) were infected with hMPV and analyzed by FACS for induction of CEACAM1 on mock (Mock) cells was set up to be 1. Figure shows one representative result out of three independent experiments. **P < 0.01, ***P < 0.001.