Table 2. Immunohistochemistry staining score of RCC and adjacent normal kidney tissue.
| Antibody | IDO13 | IDO1 | IDO1 | CD684 |
|---|---|---|---|---|
| Tissue | Endothelial cells | Neoplastic cells | Interstitial cells | Interstitial cells |
| Kidney Neg1 | 0 | 0 | 0 | n/a |
| Kidney-1 | 0 | 0 | 0 | 0.5 |
| Kidney-2 | 0 | 0 | 0 | 0.5 |
| Kidney-3 | 0 | 0 | 0 | 1 |
| Grade 22 Neg | 0 | 0 | 0 | 0 |
| Grade 2-1 | 1 | 0 | 1 | 2.5 |
| Grade 2-2 | 3 | 1 | 1 | 3 |
| Grade 2-3 | 2 | 1 | 1 | 2 |
| Grade 3 Neg | 0 | 0 | 0 | 0 |
| Grade 3-1 | 2 | 0 | 1 | 4 |
| Grade 3-2 | 2 | 0 | 1 | 5 |
| Grade 3-3 | 3 | 0 | 1 | 2.5 |
1
Neg=secondary antibody only
2
Grade of renal cell carcinoma (RCC)
3
Score for IDO1: 0=no staining, 1=1-10%, 2=10-20%, 3=20-40% staining, respectively
4
Score for CD68: 0=no staining, 1=1-10%, 2=10-20%, 3=20-30%, 4=30-40%, 5=40-50% positive interstitial cells