Table 2. Cluster mutation locations with >10% incidence across validation cohort of 170 melanoma clinical cases.
| Gene | Location | Incidence (%) |
|---|---|---|
| TERT | Promoter | 76.8 |
| BRAF | Codon 600 | 36.5 |
| DPH3 | Promoter | 27.1 |
| RPS27 | 5′UTR | 25.9 |
| C16orf59 | Promoter | 21.2 |
| RPL18A | Promoter | 18.8 |
| RPS3A | Promoter | 17.6 |
| KIAA0907 | Promoter | 17.1 |
| CCDC94 | Promoter | 17.1 |
| SLC30A6 | Promoter | 15.9 |
| UBXN8 | Promoter | 14.7 |
| MRPS31 | 5′UTR | 14.7 |
| NRAS | Codon 61 | 13.5 |
| PSMC6 | Promoter | 12.9 |
| CHCHD2 | 5′UTR | 12.9 |
| RBM22 | 5′UTR | 12.9 |
| SYF2 | Promoter | 12.4 |
| YAE1D1 | Promoter | 12.4 |
| ERGIC3 | 5′UTR | 12.4 |
| PSMD11 | Promoter | 11.8 |
| NDUFB9 | 5′UTR | 11.8 |
| CDC37 | 5′UTR | 10.6 |
| POLDIP3 | Promoter | 10.6 |
| NFIC | Intron | 10 |
| INO80B | 5′UTR | 10 |
5′UTR - 5 prime untranslated region