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. 2016 Aug 22;7(41):66769–66775. doi: 10.18632/oncotarget.11484

Figure 3. ASC-J9® reduces CD4+ T cell migration to the prostate stroma cell.

Figure 3

(A) CD4+ T cell HH (top chamber) were co-cultured with prostate stroma cell WPMY-1 (bottom chamber) for the migration assay. The scheme shows the detailed experiment setting of CD4+ T cell migration assay (left panel). 2.5 μM of ASC-J9® reduces CD4+ T cell migration compared to vehicle control using Boyden chamber transwell migration assay (right panel). (B) The pictures show the morphology of WPMY-1 after CD4+ T cell recruitment. Left panel shows WPMY-1 started to detach from the culture dish when encountering more migrated CD4+ T cells. Right panel shows normal attached WPMY-1 with less CD4+ T cells recruited.