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. 2016 Sep 14;7(41):67333–67346. doi: 10.18632/oncotarget.12024

Figure 1. Neutrophils are dysfunctional in HL.

Figure 1

Mean values ± DS of phagocytosis test in neutrophils are shown from HL patients and healthy subjects in duplicate (panel A). Mean fluorescence intensity (MFI) of CD11b in neutrophils was evaluated at diagnosis (panel B) and after 2 courses of ABVD therapy (panel C). Neutrophils isolated from 4 healthy donors in two independent experiments were incubated for 24 hours with RPMI media plus 20% of serum obtained from healthy donor or HL patients in order to evaluate any change in CD11b MFI (panel D). Gating strategy for CD11b expression on neutrophils is shown in (panel E).