Table 3. Continence-related outcomes comparison.
Outcome of interest | No. of studies | No. of patients, BNP/control | OR(95% CI) | P-Value | Study heterogeneity | Egger test (P-Value) | |||
---|---|---|---|---|---|---|---|---|---|
Chi2 | df | P-Value | I2 | ||||||
Subgroup analyses | |||||||||
BNP vs. noBNP | |||||||||
1. Continence | |||||||||
0 d | 3 | 279/232 | 3.24 [1.61, 6.52] | 0.0010 | 1.24 | 2 | 0.54 | 0% | 0.074 |
1 mo | 6 | 385/387 | 2.45 [1.32, 4.55] | 0.005 | 17.57 | 5 | 0.004 | 72% | 0.288 |
3 mo | 8 | 585/528 | 2.04 [1.39, 3.00] | 0.0003 | 13.60 | 7 | 0.06 | 49% | 0.791 |
2-4 mo | 10 | 964/837 | 2.22 [1.42, 3.47] | 0.0004 | 33.24 | 9 | 0.0001 | 73% | 0.048 |
6 mo | 8 | 582/528 | 1.72 [1.25, 2.37] | 0.0010 | 4.25 | 7 | 0.75 | 0% | 0.493 |
12 mo | 7 | 840/675 | 1.46 [1.06, 2.02] | 0.02 | 5.22 | 6 | 0.52 | 0% | 0.783 |
2. Urine leak | 4 | 511/459 | 1.07 [0.45, 2.58] | 0.88 | 2.92 | 1 | 0.09 | 66% | - |
BNP vs. BNR | |||||||||
Continence ≥12mo | 4 | 183/279 | 3.30 [1.26, 8.66] | 0.02 | 4.46 | 3 | 0.22 | 33% | 0.025 |
Overall | |||||||||
Continence >12mo | 4 | 519/451 | 3.99 [1.94, 8.21] | 0.0002 | 5.38 | 3 | 0.15 | 44% | 0.218 |
BNP vs. noBNP | 2 | 438/369 | 3.96 [1.72, 9.13] | 0.001 | 3.62 | 1 | 0.06 | 72% | - |
BNP vs. BNR | 2 | 81/82 | 4.09 [0.98, 17.11] | 0.05 | 1.75 | 1 | 0.19 | 43% | - |
Bladder neck stricture | 7 * | 758/823 | 0.49 [0.29, 0.81] | 0.006 | 5.28 | 5 | 0.38 | 5% | 0.431 |
BNP vs. noBNP | 4 | 634/529 | 0.42 [0.20, 0.89] | 0.02 | 3.25 | 2 | 0.20 | 38% | 0.112 |
BNP vs. BNR | 4 | 225/294 | 0.50 [0.26, 0.94] | 0.03 | 2.69 | 3 | 0.44 | 0% | 0.686 |
CI = confidence interval; OR = odds ratio
overlap of data
Statistically significant results are shown in bold.