Table 3. Relationship between CTCs in different chemotherapy cycle and tumor response to chemotherapy.

		Baseline and during chemotherapy
				During chemotherapy
	Any	Baseline	Any	Cycle 1	Cycle 2	Cycle 3
Disease control rate	3.72(1.86, 7.43) I2 = 49.9% P < 0.001	2.56(1.36, 4.82) I2 = 0.0% P < 0.01	5.43(1.60, 18.49) I2 = 71.1% P < 0.01	3.16(0.29, 34.14) I2 = 86.8% P > 0.05	8.52(1.66, 43.83) I2 = 0.0% P < 0.05	9.39(2.81,31.39) I2 = 0.0% P < 0.001
Objective response rate	1.37(1.11, 1.71) I2 = 59.7% P < 0.01	1.07(0.75, 1.53) I2 = 57.6% p > 0.05	1.59(1.26, 2.00) I2 = 40.8% P < 0.001	1.44(0.89, 2.31) I2 = 59.3% p > 0.05	1.71(1.00, 2.91) I2 = 32.6% P < 0.05	1.85(1.04, 3.30) I2 = 65.6% P < 0.05
HR for OS	3.83(2.49, 5.88) I2 = 2.2% P < 0.001	3.43(2.21, 5.33) I2 = 19.8% P < 0.001	/	3.83(2.49, 5.88) I2 = 7.9% P < 0.001	/	/
HR for FPS	3.34(2.58, 4.32) I2 = 0.0% P < 0.001	3.16(2.23, 4.48) I2 = 0.0% P < 0.001	/	3.78(2.33, 6.13) I2 = 11.5% P < 0.001	/	/