Table 2. significant pathways from the pathway analysis of up-regulated AD genes in expression dataset.

Classification	Pathway ID	Pathway Name	C	O	E	R	rawP	adjP
Immunity	hsa05322	Systemic lupus erythematosus	136	13	1.89	6.88	6.41E-08	1.44E-06
Immunity	hsa04670	Leukocyte transendothelial migration	116	8	1.61	4.97	2.00E-04	7.00E-04
Immunity	hsa04640	Hematopoietic cell lineage	88	6	1.22	4.91	1.40E-03	2.40E-03
Immunity	hsa04650	Natural killer cell mediated cytotoxicity	136	7	1.89	3.71	3.00E-03	4.10E-03
Immunity	hsa04666	Fc gamma R-mediated phagocytosis	94	5	1.31	3.83	1.01E-02	1.23E-02
Immunity	hsa04660	T cell receptor signaling pathway	108	5	1.5	3.33	1.76E-02	2.03E-02
Metabolism	hsa00360	Phenylalanine metabolism	17	5	0.24	21.18	2.74E-06	3.08E-05
Metabolism	hsa00500	Starch and sucrose metabolism	54	7	0.75	9.33	9.69E-06	7.27E-05
Metabolism	hsa00053	Ascorbate and aldarate metabolism	26	5	0.36	13.85	2.63E-05	1.00E-04
Metabolism	hsa00830	Retinol metabolism	64	7	0.89	7.87	3.01E-05	2.00E-04
Metabolism	hsa00040	Pentose and glucuronate interconversions	32	5	0.44	11.25	7.51E-05	3.00E-04
Metabolism	hsa00860	Porphyrin and chlorophyll metabolism	43	5	0.6	8.37	3.00E-04	9.00E-04
Metabolism	hsa00350	Tyrosine metabolism	41	5	0.57	8.78	3.00E-04	9.00E-04
Metabolism	hsa00514	Other types of O-glycan biosynthesis	46	5	0.64	7.83	4.00E-04	1.00E-03
Metabolism	hsa00982	Drug metabolism - cytochrome P450	73	6	1.01	5.92	5.00E-04	1.10E-03
Metabolism	hsa00980	Metabolism of xenobiotics by cytochrome P450	71	6	0.99	6.08	5.00E-04	1.10E-03
Metabolism	hsa00983	Drug metabolism - other enzymes	52	5	0.72	6.92	8.00E-04	1.60E-03
Metabolism	hsa00140	Steroid hormone biosynthesis	56	5	0.78	6.43	1.10E-03	2.10E-03

C, O, E, R, rawP, and adjP have been defined in Table 1.