Table 3. significant pathways from the pathway analysis of down-regulated AD genes in expression dataset.
| Classification | Pathway ID | Pathway Name | C | O | E | R | rawP | adjP |
|---|---|---|---|---|---|---|---|---|
| Immunity | hsa04062 | Chemokine signaling pathway | 189 | 9 | 2.54 | 3.54 | 1.10E-03 | 1.90E-03 |
| Metabolism | hsa00190 | Oxidative phosphorylation | 132 | 17 | 1.78 | 9.58 | 3.15E-12 | 2.91E-11 |
| Metabolism | hsa00020 | Citrate cycle (TCA cycle) | 30 | 7 | 0.4 | 17.35 | 1.19E-07 | 7.47E-07 |
| Metabolism | hsa00250 | Alanine, aspartate and glutamate metabolism | 32 | 6 | 0.43 | 13.94 | 3.88E-06 | 1.62E-05 |
| Metabolism | hsa00534 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin | 26 | 5 | 0.35 | 14.3 | 2.25E-05 | 7.70E-05 |
| Metabolism | hsa00230 | Purine metabolism | 162 | 7 | 2.18 | 3.21 | 6.60E-03 | 8.20E-05 |
C, O, E, R, rawP, and adjP have been defined in Table 1.