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. 2016 Sep 24;7(45):72733–72745. doi: 10.18632/oncotarget.12238

Figure 1. Flow diagram summarizing the analysis pipeline.

Figure 1

Blue colored boxes represent subject selection criteria. Peach colored boxes include sequencing data and variant filtering analyses. MAF refers to the SNP minor allele frequency. Remaining variants (RV) refers to the number of combined SNVs and INDELs remaining in the analysis pipeline following each filtering step. The final number of variants highlighted in bold (RV = 108) refers to the predicted damaging and likely somatic variants detected in the 57 HD-ALL patients.