Table 1. Results of CD68 and CD20 immunohistochemistry scoring.
Immune marker | CD68 n (%) | CD20 n (%) |
---|---|---|
Dichotomized total score* | < 8 vs ≥ 8 | < 5 vs ≥ 5 |
Low expression | 65 (46.1) | 50 (35.5) |
High expression | 76 (53.9) | 91 (64.5) |
Dichotomized tumor (intraepithelial) compartment score | < 2 vs ≥ 2 | < 2 vs ≥ 2 |
Low expression | 33 (23.4) | 118 (83.6) |
High expression | 108 (76.6) | 23 (16.4) |
Dichotomized stroma compartment score | < 3 vs ≥ 3 | < 2 vs ≥ 2 |
Low expression | 30 (21.3) | 46 (32.6) |
High expression | 111 (78.7) | 95 (67.4) |
Dichotomized peripheral compartment score | < 3 vs ≥ 3 | < 2 vs ≥ 2 |
Low expression | 52 (36.9) | 12 (8.5) |
High expression | 89 (63.1) | 129 (91.5) |
Dichotomized labelling (low vs high expression) based on the median value of immune marker expression. Total score accounted for all three compartment scores (tumor, stroma, periphery).