Figure 4. Cytotoxicity of CSOSA/DOX against mammospheres.

(A) The survival rates of the mammospheres measured by APH assay. *p < 0.05, n = 3. (B) Typical light photographs of mammospheres treated with formulations (CSOSA, DOX·HCl, CSOSA/DOX). The equivalent dose of DOX was 1.5 μg/mL. Scale bar, 50 μm.