Figure 6. Geridonin and paclitaxel act synergistically to inhibit the PI3K/Akt pathway in vitro through regulation of PTEN expression.
Western blot analysis after treatment of MGC 803 cells with geridonin (10 μM), paclitaxel (15 nM), or geridonin plus paclitaxel for 24 h. GAPDH was used as a loading control. #P < 0.05 versus the negative control; ##P < 0.01 versus the negative control; *P < 0.05; **P < 0.01.