Figure 5. A combination of NFκB inhibition and IR efficiently deplete CSCs.

(A) Cells were sensitized with Emetine for 24 hrs; Emetine was removed from the media before IR. Cells were collected and processed for ALDH enzymatic activity using fluorescence-activated cell sorting (FACS). (B) A combination of NFκB inhibition and IR leads to enhanced depletion of CSCs in MEC cell lines compared to radiation alone (n = 3, mean ± SD).