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. 2016 Sep 15;7(45):73618–73637. doi: 10.18632/oncotarget.12037

Table 1. IC50 values (μM) of gefitinib and erlotinib as single agents and in combination with anti-EGFR monoclonal antibodies.

Cell lines MDA-MB-231 HCC-1937 MDA-MB-468 SUM-1315
Gefitinib 16.5 16.1 10.0 25.3
Gefitinib + Cetuximab 18.3 20.0 1.5 4.1
Gefitinib + Panitumumab 22.3 17.0 7.9 5.9
Erlotinib 7.0 20.0 15.9 -
Erlotinib + Cetuximab 8.4 20.0 2.9 1.1
Erlotinib + Panitumumab 11.2 14.1 10.0 1.7