Table 2. The list of immunohistochemistry (IHC) proteins stained from cancerous tissues which were dissected from 131 local lung adenocarcinoma patients, their criteria for abnormal IHC and the factions of these patients with abnormal IHC.
| No. | Protein name | Criterion of abnormality | % of patients with abnormal IHC |
|---|---|---|---|
| 1 | ABL1(C)a | ≧ 2+ | 24 |
| 2 | AURKB(C) | ≧ 1+ | 91 |
| 3 | BCR(C) | ≧ 2+ | 27 |
| 4 | BRCA1(C) | < 1+ | 77 |
| 5 | BRCA2(C) | < 2+ | 67 |
| 6 | BRCA2(N)a | < 2+ | 19 |
| 7 | CDH1(M)a | ≧ 70% | 62 |
| 8 | CSNK1E(C) | <2+ | 94 |
| 9 | CTNNB1(N) | ≧ 1+ | 6 |
| 10 | EGFR(C) | ≧ 1+ | 19 |
| 11 | FEN1(C) | ≧ 2+ | 58 |
| 12 | FEN1(N) | ≧ 2+ | 50 |
| 13 | MSH2(C) | < 1+ | 31 |
| 14 | MSH2(N) | <1+ | 20 |
| 15 | MYC(N) | ≧ 2+ | 42 |
| 16 | PARP1(N) | ≧ 1+ | 87 |
| 17 | POLB(N) | ≧ 1+ | 91 |
| 18 | RAD54B(N) | ≧ 1+ | 33 |
| 19 | RB1(N) | < 1+ | 55 |
| 20 | SGK2(C) | < 2+ | 96 |
| 21 | SKP2(C) | ≧ 2+ | 10 |
| 22 | TP53(N) | ≧ 1+ | 51 |
| 23 | WNT5A(C) | ≧ 1+ | 60 |
a
The notation (C), (N) and (M) represent cytoplasm, nucleus and membrane, respectively.