Table 4. The association between TERT rs2853676 polymorphism and prognosis outcome by multivariate analysis.

		Genotype	HR	95% CI	P-value
Grade I-II	OS	G/G	1
		A/G	0.873	0.673 - 1.134	0.309
		A/A	0.913	0.493 - 1.689	0.772
	PFS	G/G	1
		A/G	0.848	0.656 - 1.096	0.207
		A/A	0.916	0.519 - 1.617	0.762
	OS	G/G	1
		A/A + A/G	0.878	0.682 - 1.128	0.309
	PFS	G/G	1
		A/A + A/G	0.856	0.67 - 1.094	0.215
Grade III-IV	OS	G/G	1
		A/G	0.735	0.528 - 1.024	0.068
		A/A	0.924	0.492 - 1.736	0.807
	PFS	G/G	1
		A/G	0.716	0.515 - 0.995	0.047
		A/A	0.852	0.456 - 1.595	0.617
	OS	G/G	1
		A/A + A/G	0.76	0.555 - 1.04	0.087
	PFS	G/G	1
		A/A + A/G	0.735	0.538 - 1.004	0.053
Total	OS	G/G	1
		A/G	0.817	0.666 - 1.002	0.052
		A/A	0.944	0.611 - 1.458	0.794
	PFS	G/G	1
		A/G	0.803	0.656 - 0.982	0.032*
		A/A	0.921	0.607 - 1.398	0.699
	OS	G/G	1
		A/A + A/G	0.832	0.685 - 1.011	0.064
	PFS	G/G	1
		A/A + A/G	0.818	0.675 - 0.99	0.040*

Notes: P-values based on the Wald test;

^*p-value < 0.05 indicates statistical significance.

Abbreviations: HR: hazard ratios; CI: confidence intervals; OS: Overall Survival; PFS: Progression-free Survival.