Table 2. Clinicopathological and molecular parameters of HGG patients in GSE16011 dataset (n = 210).
| Variable | Total | Low risk score (n = 105) | High risk score (n = 105) | p value | |
|---|---|---|---|---|---|
| Age at diagnosis | < 45 | 74 | 50 | 24 | < 0.05 |
| ≥ 45 | 136 | 55 | 81 | ||
| Gender | Male | 139 | 64 | 75 | > 0.05 |
| Female | 71 | 41 | 30 | ||
| Preoperative KPS score | < 80 | 57 | 28 | 29 | > 0.05 |
| > 80 | 144 | 72 | 72 | ||
| NA | 9 | 5 | 4 | ||
| Histology | AA | 13 | 11 | 2 | < 0.05 |
| AO | 42 | 33 | 9 | ||
| AOA | 23 | 20 | 3 | ||
| GBM | 132 | 41 | 91 | ||
| IDH1 mutation | Mut | 59 | 42 | 17 | < 0.05 |
| WT | 108 | 45 | 63 | ||
| NA | 43 | 23 | 21 | ||
| Extent of surgery | Total | 67 | 32 | 35 | > 0.05 |
| Subtotal | 114 | 64 | 50 | ||
| NA | 29 | 12 | 17 | ||
| Radiotherapy | Yes | 175 | 86 | 89 | Not available |
| No | 0 | 0 | 0 | ||
| NA | 35 | 19 | 16 | ||
| Chemotherapy | Yes | 26 | 13 | 13 | > 0.05 |
| No | 150 | 75 | 75 | ||
| NA | 34 | 17 | 17 |