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. 2016 Oct 6;7(45):74217–74226. doi: 10.18632/oncotarget.12487

Figure 7. PIK3R2 participates in proliferation and apoptosis of RASFs induced by miR-126.

Figure 7

A. Western blot detecting changes in expression for PIK3R2 and proteins in the PI3K/AKT signaling pathway. B. MTT assay measuring cell proliferation. C. Flow cytometry detecting apoptosis rate for cells in RASFs transfected with miR-126 and control cells. RASFs, rheumatoid arthritis synovial fibroblasts; miR-126, microRNA-126; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; NC, normal control; a, blank group; b, anti-miR-126 group; c, anti-miR-126+ PIK3R2 siRNA group; *, compared with the NC group, P < 0.05; #, compared with the anti-miR-126 group, P < 0.05.