Table 3. Clinicopathologic data for each familial pancreatic cancer patient with a deleterious germline mutation.
Patient ID | Age | Gender | Gene with pathogenic mutation | UICC-stage | Smoking history (Brinkman index) | Tumor location | Family history of other cancer in FDRs | Past medical history of other cancer | Diabetes mellitus | Chronic pancreatitis | |
---|---|---|---|---|---|---|---|---|---|---|---|
1 | NCCH-3 | 62 | Male | MLH1 | IV | + (630) | Body/tail | - | - | - | - |
2 | NCCH-5 | 55 | Female | ATM | IV | - | Body/tail | Father (Gastric cancer, Colon cancer, Prostate cancer) | - | - | - |
3 | NCCH-14 | 45 | Female | PALB2 | IB | - | Body/tail | - | - | - | - |
4 | NCCH-16 | 67 | Female | ATM | IIB | + (510) | Head | - | Breast cancer, Ureter cancer | - | - |
5 | NCCH-22 | 58 | Female | PALB2 | IIB | - | Body/tail | Father (Brain tumor) | - | - | - |
6 | NCCH-104 | 52 | Female | BRCA2 | IB | - | Body/tail | - | - | - | - |
7 | TWMU-1-1 | 69 | Male | BRCA2 | III | - | Body/tail | - | - | - | - |
8 | TWMU-7-1 | 64 | Male | BRCA2 | IB | - | Head | - | - | + | - |