Figure 2. Suppression of NRIP1 inhibited the growth and induced apoptosis of HaCaT cells.
A. shNRIP1 suppressed the NRIP1 expression in HaCaT cells. B. MTT assay showed shNRIP1 reduced the growth of HaCaT cells significantly at the 48h, 72h, 96h and 120h time points (p<0.05) after being seeded, respectively. C&D. Annexin V showed that shNRIP1 induced the apoptosis of HaCaT cells significantly (p<0.001). E. Western blot result showed that the expression of p65 was remarkably reduced by shNRIP1 transfection in HaCaT cells.