Table 1. Univariate and multivariate analysis of clinicopathologic variables in relation to overall survival after curative operation.

Parameter			Univariate analysis		Multivariate analysis
		Number	Hazard ratio(95% CI)	P value	Hazard ratio(95% CI)	P value
Gender	male	100
	female	59	1.307(0.887-1.926)	0.176
Age	<65	86
	≥65	73	1.730(1.167-2.567)	0.006	1.493(1.045-2.132)	0.028
Albumin(g/dL)	<3.5	18
	≥3.5	141	1.430(0.754-2.711)	0.274
CEA(ng/mL)	<5	117
	≥5	42	2.696(1.608-4.518)	<0.0001	1.725(1.155-2.575)	0.008
CA125(U/mL)	<35	128
	≥35	31	1.694(0.973-2.947)	0.062
CA19-9(U/mL)	<39	34
	≥39	125	1.360(0.811-2.281)	0.244
PLR	<130.96	62
	≥130.96	97	1.217(0.720-2.057)	0.463
NLR	<2.12	53
	≥2.12	106	1.226(0.745-2.019)	0.422
ABO blood type	A	55
	AB	20	1.499(0.779-2.884)	0.226
	B	50	0.633(0.382-1.049)	0.076
	O	34	0.992(0.597-1.647)	0.975
Location	uncinate process	52
	head	71	1.727(1.078-2.768)	0.023
	body and tail	36	1.358(0.808-2.281)	0.248
Differentiation	poor	20
	poor to moderate	56	0.858(0.440-1.672)	0.652
	moderate	69	0.586(0.300-1.146)	0.118
	well to moderate	12	0.598(0.229-1.561)	0.294
	well	2	1.215(0.240-6.165)	0.814
Diameter(cm)	<3.5	69
	≥3.5	90	1.757(1.143-2.700)	0.01
T	1	12
	2	43	1.988(0.782-5.055)	0.149	2.133(0.888-5.122)	0.09
	3	103	2.281(0.904-5.753)	0.081	3.263(1.414-7.528)	0.006
	4	4	4.906(1.159-20.767)	0.031	7.314(2.008-26.644)	0.003
Lymph node status	Negative	70
	Positive	89	1.586(1.035-2.431)	0.034	1.751(1.208-2.538)	0.003

NLR, Neutrophil-to-lymphocyte ratio; PLR, platelet-to-lymphocyte ratio