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. 2016 Sep 18;7(44):71255–71273. doi: 10.18632/oncotarget.12104

Figure 3. GILT restricts HIV-1 replication.

Figure 3

A. TE671/CD4 cells were transfected with pcDNA3.1, wild type GILT, or the GILT DCS mutant, and inoculated with the HIV-1 LAI strain. HIV-1 Gag p24 levels in the supernatants were measured. This experiment was repeated three times, and a representative result is shown. B. Primary MDMs transduced by the empty or shGILT-expressing lentivirus vector were inoculated with the HIV-1 AD8 strain. The amounts of Gag p24 in the supernatants were measured (n = 4). The amounts of p24 in the empty vector-transduced MDMs 16 days after the inoculation are always set to 1, and relative values are indicated. Asterisks indicate statistically significant differences.