Table 2. Immunological parameters of mice immunized with therapeutic peptide vaccines.

Groups	PBS	AFP-P	HSP70-P	HSP70-P/AFP-P
Spotsa (× 106 cells)	17.35±7.42	18.32±7.55#	17.74±8.27$	478.65±16.75‡*
Granzymeb (pg/ml)	8.47±2.26	8.37±2.34#	8.49±2.63$	104.73±8.62‡*
Perforinc (pg/ml)	7.78±2.32	8.25±2.45#	8.38±2.54$	97.78±7.74‡*
AFP Absd (μg/ml)	1.40±0.38	1.41±0.26#	1.43±0.25$	14.76±3.22‡*
HSP70 Abse (μg/ml)	1.41±0.22	1.42±0.32#	1.46±0.34$	1.48±0.37‡*

^aAFP-specific IFN-γ-secreting CD8⁺ T cells;

^bGranzyme B released from natural killer cells;

^cPerforin released from natural killer cells;

^dAFP-P specific antibodies in mice;

^eHSP70-specific antibodies in mice

^#P>0.05, vs PBS group;

^$P>0.05, vs PBS group;

^‡P<0.01, vs AFP-P group;

^*P<0.01, vs HSP70-P group.