Table 1. Clinical characteristics of newly diagnosed AML patients.
| Characteristics | NPM1-wt (n = 8) | NPM1-mut (n = 4) |
|---|---|---|
| Sex, Male/Female | 3/5 | 2/2 |
| Median age, y (range) | 38.5 (26–58) | 53 (43–72) |
| Median WBC, × 109/L | 17.5 (0.7–280) | 23.5 (1.3–295) |
| Median platelets, × 109/L | 54.7 (8.0–455.0) | 61.4 (10.0–655.0) |
| FAB classification | ||
| M1 | 1 | 2 |
| M2 | 1 | 0 |
| M3 | 4 | 0 |
| M4 | 2 | 1 |
| M5 | 0 | 1 |
| Karyotype | ||
| Normal | 1 | 4 |
| t (8;21) | 1 | 0 |
| t (15;17) | 4 | 0 |
| inv (16) | 2 | 0 |
| Gene mutations | ||
| FLT3/ITD (+/−) | 2/6 | 2/2 |
| WT1 (+/−) | 3/5 | 3/1 |
| KIT (+/−) | 1/7 | 3/1 |
Note: AML: acute myeloid leukemia; NPM1-wt: NPM1-wild type; NPM1-mut: NPM1- mutation; WBC: white blood cell; FAB classification: French-American-British classification, a classification of acute leukemia produced by three-nation joint collaboration.