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. 2016 Sep 26;7(44):71594–71607. doi: 10.18632/oncotarget.12261

Figure 4. C-C7 recognizes blood vessels and macrophages in human atherosclerosis.

Figure 4

Immunostainings of surgical samples of atherosclerotic lesions from carotid arteries with CC7 (A, D) the macrophage marker CD68 (B, E) and the endothelial marker CD31 (C) and anti-dynactin-1 p150Glued (F, the anti-dynactin antibody was implemented in thee staining based on identification of dynactin as a binding partner of C-C7). (A–C) and (D–F) represent serial sections from two different lesions. Note the similarity in staining profiles for C-C7 and dynactin P150Glued (D and F, respectively). Tissues in A–C were stained with AEC, tissues in (D–F) with DAB. NC = nectrotic core, I = intima, L = lumen. Bars correspond to 100 μM in panels (A–C) and to 50 μm in panels (D–F).