Table 1. The IC50 of UA on human cancer cell lines (μM, from MTT assay, 48 h treatment).
| Compounds | MDA-MB-231 | SW480 | MG63 | PC3 | DU145 | HCT116 | 143B | MDA-MB-468 |
|---|---|---|---|---|---|---|---|---|
| UA | 2.669 | 8.058 | 19.616 | 6.026 | 4.283 | 5.297 | 6.220 | 4.054 |
| ADR | 0.294 | 5.782 | 7.061 | 0.416 | 0.150 | 0.702 | 0.435 | 2.323 |
| 5-Fu | > 500 | > 500 | > 500 | > 500 | 163.686 | > 500 | > 500 | > 500 |
| Carb | > 100 | > 100 | > 100 | > 100 | > 100 | > 100 | 37.629 | > 100 |
| CPT | 1.226 | 5.569 | 0.265 | 0.025 | 0.03 | 0.147 | 0.022 | 0.027 |
| Taxol | 12.809 | 38.682 | 41.107 | > 100 | < 1E−5 | 4E−4 | 4E−4 | 2.381 |
| VCR | 8.718 | > 100 | 29.669 | > 100 | 6.27 E−5 | 1.34 E−4 | 1.30 E−5 | 1E−4 |