Table 3A. Downregulated genes by si-MTDH in “Focal adhesion pathway”.
Entrez gene ID | Gene symbol | Description | si-MTDH transfectant (fold-change) |
GSE19188 (fold-change) |
|
---|---|---|---|---|---|
siRNA1 | siRNA2 | ||||
1290 | COL5A2 | collagen, type V, alpha 2 | 0.02 | −0.07 | 3.55 |
3688 | ITGB1 | integrin, beta 1 | −2.28 | −0.05 | 2.64 |
2317 | FLNB | filamin B, beta | −2.20 | −2.01 | 2.43 |
7422 | VEGFA | vascular endothelial growth factor A | −2.06 | 0.36 | 1.99 |
3915 | LAMC1 | laminin, gamma 1 (formerly LAMB2) | −3.22 | 0.18 | 1.61 |
1956 | EGFR | epidermal growth factor receptor | −2.30 | −0.88 | 1.50 |
3371 | TNC | tenascin C | −4.17 | −0.37 | 1.46 |
5501 | PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | −0.60 | −2.04 | 1.42 |
5500 | PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | −4.54 | −2.17 | 1.37 |
10000 | AKT3 | v-akt murine thymoma viral oncogene homolog 3 | −2.73 | −2.19 | 1.37 |
394 | ARHGAP5 | Rho GTPase activating protein 5 | −2.63 | 0.00 | 1.36 |
208 | AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.22 | −2.70 | 1.34 |
5578 | PRKCA | protein kinase C, alpha | −0.26 | −3.17 | 1.30 |
3914 | LAMB3 | laminin, beta 3 | −2.31 | −0.20 | 1.04 |