Table 1. Correlations between clinicopathological variables and A) Intratumoral CD66b⁺ cells in resected primary tumors of NSCLC patients in the overall cohort and stratified into the SCC and ADC subgroups (chi-square test and fisher exact test, N = 536, 289 and 201 respectively); B) Intratumoral CD66b⁺ cells in lymph-node tissue from N+ NSCLC patients in the overall cohort and stratified into the SCC and ADC subgroups (chi-square test and fisher exact test, N = 172, 91 and 68 respectively).

	A									B
	All			SCC			ADC			All			SCC			ADC
	Low	High	P	Low	High	P	Low	High	P	Low	High	P	Low	High	P	Low	High	P
Age			0.535			0.223			0.023			1.000			0.284			0.367
≤65	129	85		65	38		54	39		41	17		22	6		18	10
>65	187	108		96	79		71	24		42	17		18	11		17	5
Gender			0.221			0.158			0.522			0.130			0.706			0.069
Female	92	67		35	35		48	28		28	6		8	2		17	3
Male	224	126		126	82		77	35		55	28		32	15		18	12
ECOG			0.092			0.189			0.394			0.407			0.432			1.000
0	185	113		88	65		75	42		48	15		22	6		20	9
1	115	61		65	40		43	16		28	15		15	9		11	5
2	16	19		8	12		7	5		7	4		3	2		4	1
Smoking			0.376			1.000			0.497			0.931			0.299			0.175
Never	12	3		4	2		7	1		3	1		2	0		1	1
Previous	200	124		101	74		77	40		49	21		25	8		20	12
Present	104	66		54	41		41	22		31	12		13	9		14	2
Weight loss			0.061			0.183			1.000			0.195			0.058			0.654
<10%	291	167		147	100		116	58		76	28		38	13		30	14
≥10%	25	25		14	17		9	5		7	6		2	4		5	1
Surgical procedure			1.000			0.276			0.867			0.703			1.000			0.746
Wedge/Lobectomy	229	140		103	83		100	49		44	16		16	7		24	9
Pulmonectomy	87	53		58	34		25	14		39	18		24	10		11	6
Margins			0.357			0.031			1.000			0.131			0.428			0.152
Free	286	180		138	110		118	60		75	27		35	13		33	12
Not free	30	13		23	7		7	3		8	7		5	4		2	3
tStage			0.011			0.119			0.431			0.064			0.495			0.371
IA	48	22		23	13		23	9		6	1		3	1		3	0
IB	60	30		27	19		27	10		15	1		5	0		7	1
IIA	120	58		57	30		50	23		31	13		15	6		15	7
IIB	43	30		29	22		10	7		12	6		7	5		4	1
III	42	50		23	32		14	13		15	13		7	5		6	6
IV	3	3		2	1		1	1		4	0		3	0
nStage			0.072			0.032			0.607			0.584			0.315			1.000
0	204	143		101	90		81	45
1	76	36		46	23		27	10		55	25		30	15		21	9
2	36	14		14	4		17	8		28	9		10	2		14	6
pStage			0.002			0.061			0.070			0.229			0.386			0.548
IA	81	47		36	30		39	17
IB	70	44		32	23		28	16
IIA	82	33		50	25		26	7		36	10		19	6		15	4
IIB	30	41		19	27		8	12		6	5		4	4		2	1
IIIA	53	28		24	12		24	11		41	19		17	7		18	10
Histology			0.096									0.908
SCC	161	117								40	17
ADC	125	63								35	15
NOS	30	13								8	2
Differentiation			0.674			0.851			0.083			0.655			0.794			0.236
Poor	132	84		58	40		44	31		41	20		15	7		18	11
Moderate	143	89		87	63		56	26		37	13		22	10		15	3
Well	41	20		16	14		25	6		5	1		3	0		2	1
Vascular infiltration			0.493			0.218			1.000			0.686			0.752			1.000
No	253	161		124	98		106	54		58	25		27	13		27	11
Yes	61	32		37	19		17	9		25	8		13	4		8	3

Abbreviations: SCC, squamous cell carcinoma; ADC, adenocarcinoma; ECOG, Eastern Cooperative Oncology Group; NOS, not otherwise specified