Table 1. Top 25 genes up regulated in LP-DLBCL compared with conventional DLBCL.
Fold change | p-value | FDR | Gene Symbol | Gene Description |
---|---|---|---|---|
4.8 | 0.0014 | 0.0331 | GZMK | granzyme K (granzyme 3; tryptase II) |
3.4 | 0.0007 | 0.0251 | GBP1 | guanylate binding protein 1, interferon-inducible |
3.4 | 0.0012 | 0.0322 | SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
3.1 | 0.0014 | 0.0331 | MT1H | metallothionein 1H |
3.0 | 0.0021 | 0.0409 | GBP5 | guanylate binding protein 5 |
3.0 | 0.0001 | 0.0086 | SLAMF7 | SLAM family member 7 |
2.9 | 0.0004 | 0.0180 | C1QA | complement component 1, q subcomponent, A chain |
2.8 | 0.0015 | 0.0331 | PYHIN1 | pyrin and HIN domain family, member 1 |
2.8 | 0.0002 | 0.0143 | GIMAP4 | GTPase, IMAP family member 4 |
2.7 | 0.0008 | 0.0265 | CD2 | CD2 molecule |
2.6 | 0.0010 | 0.0294 | GBP2 | guanylate binding protein 2, interferon-inducible |
2.6 | 0.0009 | 0.0278 | LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) |
2.6 | 0.0046 | 0.0620 | SCARNA8 | small Cajal body-specific RNA 8 |
2.5 | 0.0003 | 0.0179 | WARS | tryptophanyl-tRNA synthetase |
2.5 | 0.0000 | 0.0086 | STOM | stomatin |
2.5 | 0.0014 | 0.0331 | SCARNA6 | small Cajal body-specific RNA 6 |
2.5 | 0.0012 | 0.0322 | STAT1 | signal transducer and activator of transcription 1, 91kDa |
2.4 | 0.0005 | 0.0227 | SCARNA10 | small Cajal body-specific RNA 10 |
2.4 | 0.0000 | 0.0086 | FYN | FYN proto-oncogene, Src family tyrosine kinase |
2.4 | 0.0007 | 0.0251 | SNX10 | sorting nexin 10 |
2.3 | 0.0092 | 0.0937 | CD3D | CD3d molecule, delta (CD3-TCR complex) |
2.3 | 0.0039 | 0.0574 | CD3G | CD3g molecule, gamma (CD3-TCR complex) |
2.3 | 0.0073 | 0.0815 | SOD2 | superoxide dismutase 2, mitochondrial |
2.3 | 0.0003 | 0.0179 | RNF213 | ring finger protein 213 |
2.3 | 0.0001 | 0.0101 | CST7 | cystatin F (leukocystatin) |
FDR, false discovery rate