Table 2. Prognostic factors for DFS and OS by univariate analysis.
| Variables | n | DFS | P | OS | P | ||||
|---|---|---|---|---|---|---|---|---|---|
| 1-yr | 3-yrs | 5-yrs | 1-yr | 3-yrs | 5-yrs | ||||
| Gender | |||||||||
| Male | 271 | 43.2% | 29.9% | 26.0% | 0.154 | 70.1% | 44.6% | 36.8% | 0.032 |
| Female | 32 | 56.3% | 37.5% | 37.5% | 81.3% | 59.4% | 56.3% | ||
| Age(yrs) | |||||||||
| <60 | 230 | 43.9% | 32.2% | 29.5% | 0.457 | 70.9% | 47.4% | 39.9% | 0.430 |
| ≥60 | 73 | 46.6% | 26.0% | 20.0% | 72.6% | 42.5% | 35.5% | ||
| HBsAg | |||||||||
| Positive | 266 | 41.4% | 28.9% | 25.0% | 0.02 | 69.2% | 44.4% | 37.5% | 0.075 |
| Negative | 37 | 67.6% | 43.2% | 43.2% | 86.5% | 59.5% | 48.6% | ||
| AFP(μg/L) | |||||||||
| < 200 | 132 | 54.5% | 38.6% | 36.3% | < 0.001 | 78.8% | 53.0% | 46.2% | 0.006 |
| ≥200 | 171 | 36.8% | 24.6% | 20.3% | 65.5% | 40.9% | 33.2% | ||
| Hb(g/L) | |||||||||
| ≤120 | 48 | 31.2% | 16.7% | 16.7% | 0.052 | 68.7% | 33.3% | 29.2% | 0.222 |
| >120 | 255 | 47.1% | 34.1% | 29.2% | 71.8% | 48.6% | 40.7% | ||
| WBC(×109) | |||||||||
| < 10 | 271 | 45.4% | 31.4% | 27.5% | 0.588 | 72.3% | 46.1% | 39.0% | 0.977 |
| ≥ 10 | 32 | 37.5% | 25.0% | 25.0% | 62.5% | 46.9% | 37.5% | ||
| AST(U/L) | |||||||||
| < 80 | 150 | 57.3% | 41.3% | 37.8% | < 0.001 | 83.3% | 58.7% | 50.6% | < 0.001 |
| ≥ 80 | 153 | 32.0% | 20.3% | 16.9% | 59.5% | 34.0% | 27.4% | ||
| Neutrophil(×109) | |||||||||
| < 3.94 | 168 | 49.4% | 35.1% | 30.8% | 0.018 | 78.6% | 51.2% | 44.0% | 0.032 |
| ≥ 3.94 | 135 | 38.5% | 25.2% | 22.8% | 62.2% | 40.0% | 32.6% | ||
| CLIP score | |||||||||
| 0-2 | 217 | 55.3% | 39.2% | 34.4% | < 0.001 | 80.6% | 56.2% | 48.8% | < 0.001 |
| 3-5 | 86 | 17.4% | 9.3% | 9.3% | 47.7% | 20.9% | 13.4% | ||
| TNM | |||||||||
| I | 175 | 52.0% | 36.6% | 32.4% | 0.001 | 77.7% | 54.3% | 47.3% | < 0.001 |
| II-III | 128 | 34.4% | 22.7% | 20.1% | 62.5% | 35.2% | 27.3% | ||
| Cirrhosis | |||||||||
| No | 66 | 40.9% | 27.3% | 24.2% | 0.454 | 75.8% | 45.5% | 37.9% | 0.803 |
| Yes | 237 | 45.6% | 31.6% | 28.1% | 70.0% | 46.4% | 39.2% | ||
HBsAg: hepatitis B surface antigen; AFP:alpha-fetoprotein; Hb: hemoglobin; WBC: white blood cell; AST: aspartate aminotransferase ratio index; CLIP: cancer of the liver Italian program; TNM: Tumor Node Metastasis.