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. 2016 Jul 26;7(44):72276–72289. doi: 10.18632/oncotarget.10848

Table 3. Prognostic factors for DFS and OS by univariate analysis.

PVTT
No 250 51.6% 35.2% 31.4% < 0.001 78.8% 52.0% 44.7% < 0.001
Yes 53 11.3% 9.4% 7.5% 35.8% 18.9% 11.0%
Tumor number
Single 215 53.5% 38.1% 33.9% < 0.001 77.0% 54.9% 48.6% < 0.001
Multiple 88 22.7% 12.4% 10.6% 56.8% 26.3% 16.7%
Tumor size(cm)
< 5 105 68.6% 51.4% 43.5% < 0.001 88.6% 68.6% 60.0% < 0.001
≥5 198 31.8% 19.7% 18.7% 62.1% 34.3% 27.7%
Complication
 No 258 44.6% 32.2% 28.1% 0.424 72.5% 46.5% 40.2% 0.361
 Yes 45 44.4% 22.2% 22.2% 64.4% 44.4% 30.8%
Tumor differentiation
I-II 235 48.5% 34.0% 30.5% 0.003 73.6% 48.9% 42.9% 0.006
III-IV 68 30.9% 19.1% 16.2% 63.2% 36.8% 24.8%
Resection margin(cm)
< 2 171 42.1% 26.9% 23.2% 0.186 70.8% 41.5% 34.4% 0.069
≥2 131 47.3% 35.1% 31.9% 71.8% 51.9% 44.2%
Intraoperative blood loss(ml)
≤ 1000 237 48.9% 34.6% 31.0% < 0.001 76.4% 50.6% 43.8% < 0.001
> 1000 66 28.8% 16.7% 13.6% 53.0% 30.3% 21.0%
ANRI
≤ 7.8 92 59.8% 46.7% 43.3% < 0.001 81.5% 62.0% 55.4% < 0.001
> 7.8 211 37.9% 23.7% 20.2% 66.8% 39.3% 31.6%
NLR
≤ 2 223 48.9% 35.9% 31.7% < 0.001 75.3% 53.4% 45.7% < 0.001
> 2 80 32.5% 16.2% 14.9% 60.0% 26.3% 20.0%
APRI
≤ 1.68 104 57.7% 41.3% 38.3% < 0.001 82.7% 59.6% 52.9% < 0.001
> 1.68 199 37.7% 25.1% 21.4% 65.3% 39.2% 31.5%
PLR
≤ 115 173 50.3% 35.8% 30.5% 0.025 75.7% 35.0% 45.6% 0.005
> 115 130 36.9% 23.8% 23.1% 65.4% 35.4% 29.9%
ALRI
≤ 20 135 57.0% 42.2% 38.5% < 0.001 81.5% 60.7% 54.1% < 0.001
> 20 168 34.5% 21.4% 18.0% 63.1% 34.5% 26.5%

PVTT: portal vein tumor thrombus; ANRI, Aspartate aminotransferase/neutrophil count ratio index; NLR: neutrophil/lymphocyte ratio index; APRI: aspartate aminotransferase/platelet count ratio index; PLR: platelet/lymphocyte ratio index; ALRI: aspartate aminotransferase/Lymphocyte count ratio index.