Table 2. Contra-indicators observed in cynomolgus macaques of Mauritian origin following aerosol infection with M. tuberculosis.

Animal I. D.	Estimated Retained Dose M. tuberculosis	Indicators observed post challenge. (week post challenge indicator recorded)		Indicators observed prior to euthanasia
		Respiration rate	Cough	Behaviour	Eating / drinking	Respiration rate Under sedation	Other indicators
M982B	236	Rapid	Yes	Depressed withdrawn	No / No	Rapid / Shallow	Very ruffled coat. Thin
		(5–6)	(8)
I131B	232	Rapid	Yes	Depressed	No / No	Rapid / Shallow	Very ruffled coat
		(5–6)	(5)
M651	221	Rapid	No	Normal	No / No	Rapid / Laboured	Ruffled coat, Thin
		(5–6)
M284D	75	Rapid	Yes	Normal	Normal	Rapid / Shallow	NAD
		(6–10)	(6, 7, 8)
I319DB	64	Rapid	Yes	Normal	Normal	Rapid laboured	NAD
		(7–12)	(6, 7, 8)
I347G	48	Rapid	Yes	Normal	Normal	Rapid / Shallow	NAD
		(6–12)	(6, 7, 8)
M054E	43	Rapid	Yes	Normal	Normal	Normal	NAD
		(7–12)	(6, 7, 8)
M064D	35	Rapid	Yes	Normal	Normal	Normal	NAD
		(7–12)	(6, 7, 8)
M988E	22	Rapid	Yes	Depressed Withdrawn	Normal	Rapid	NAD
		(7–12)	(6, 7, 8)

NAD: No abnormalities detected.