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. 2017 Mar 8;12(3):e0172089. doi: 10.1371/journal.pone.0172089

Table 3. Cox regression analysis of risk factors for hypertension development.

Univariate model Multivariate model
Variable Unadjusted HR (95% CI) p value Adjusted HR (95% CI) p value
Age (per 10-year increase) 1.33 (1.10–1.60) 0.004 1.34 (1.07–1.68) 0.010
Female gender 0.74 (0.47–1.15) 0.180 0.63 (0.37–1.09) 0.097
BMI (per 5 kg/m2 increase) 1.32 (1.02–1.71) 0.037 1.45 (1.07–1.99) 0.018
eGFR (< 60 ml/min/1.73 m2) 3.74 (1.71–8.18) 0.001 3.79 (1.60–8.99) 0.003
Smoking 0.81 (0.30–2.22) 0.682 0.61 (0.19–2.04) 0.427
Alcohol consumption 0.57 (0.28–1.14) 0.112 0.50 (0.23–1.12) 0.091
CD4 count (per 25 cell/mm3 increase) 0.98 (0.95–1.01) 0.194 0.98 (0.94–1.02) 0.300
ART exposure 1.04 (0.56–1.93) 0.906 0.95 (0.42–2.13) 0.907

BMI: body mass index; eGFR: estimated glomerular filtration rate; ART: antiretroviral therapy.