Table 5. Subgroup analysis for hsa05322: histological subtypes, sex, age, smoking.

hsa05322: SLE	META-GSA	Gene	Location	concordance	significance
	pGS			${\overline{\mathit{P}\mathit{D}\mathit{R}}}_{\mathit{g}}$	pgene
AdenoLC	0.0030	HIST2-1q21.2	1q21.2	-0.6	0.1666
SqCLC	0.0376	H2AFV	7p13	0.5	0.7209
SCLC	0.0626	C1QA	1p36.12	-0.5	0.7101
		HIST2-1q21.2	1q21.2	-0.5	0.0577
		ELANE	19p13.3	0.5	0.4864
		HIST1-6p22.2	6p22.2	0.5	0.2177
		HIST1-6p22.2	6p22.2	0.5	0.2177
LCLC	0.2056	--
male	0.1453	HIST1H3C	6p22.2	-0.5	0.3726
female	0.0112	HIST1H2AL	6p22.1	0.5	0.1229
old (>50)	0.0002	HIST1-6p22.1a	6p22.1	-0.7	0.0054
		HIST1-6p22.1b	6p22.1	0.5	0.1578
		C2	6p21.3	0.5	0.0013
		H2AFV	7p1	0.6	0.4005
young (≤50)	0.0588	--
current smokers	0.3563	HIST1-6p22.1a	6p22.1	0.4	0.1720
		H3F3C	12p11.21	0.4	0.5821
		HIST3H3	1q42	0.4	0.6468
		HIST1-6p22.1b	6p22.1	0.4	0.2028
		HIST1-6p22.1c	6p22.1	0.4	0.3375
former smokers	0.4691	--
ever smokers	0.5132	HIST1-6p22.1a	6p22.1	0.5	0.0462
		HIST1-6p22.1c	6p22.1	0.5	0.1587
never smokers	0.5429	FCGR3A	1q23	-0.5	0.2300
		CTSG	14q11.2	-0.5	0.3403

Listed are genes, respectively regions containing genes with $abs\left({\overline{\mathit{P}\mathit{D}\mathit{R}}}_{\mathit{g}}\right)\ge 0.5$.

HIST2-1q21.2: HIST2H2AA3 / HIST2H2AA4 / HIST2H3C / HIST2H4B.

HIST3-1q42: HIST3H2A / HIST3H2BB / HIST3H3.

HIST1-6p22.1a: HIST1H4K / HIST1H2AK / HIST1H2AL / HIST1H2BM / HIST1H2BN / HIST1H3I / HIST1H4L / HIST1H3J / HIST1H4J (27.800K).

HIST1-6p22.1b: HIST1H2AG / HIST1H2BK (27.150 K).

HIST1-6p22.1c: HIST1H2BI / HIST1H3G / HIST1H4H (26.280 K).

HIST1-6p22.2: HIST1H3E / HIST1H2AE / HIST1H2BG / HIST1H4E (26.200 K).

The numbers in brackets are the approximate locations according to dbGENE.