Table 3. Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of COPD based on self-reported data and based on Electronic Medical Records compared with COPD based on spirometry–LLN and GOLD-definition.

Agreement between the three different data sources was determined with Cohen’s Kappa.

	COPD-LLN		COPD-GOLD
	Self-report	EMR	Self-report	EMR
Sensitivity	0.30	0.26	0.21	0.19
Specificity	0.97	0.99	0.97	0.99
PPV	0.38	0.52	0.50	0.71
NPV	0.96	0.96	0.91	0.91
Cohen’s Kappa (95% CI)	0.30 (0.21–0.39)	0.31 (0.22–0.41)	0.25 (0.18–0.32)	0.26 (0.19–0.34)

The agreement between GOLD-definition cases and LLN-definition cases was ĸ = 0.65 (0.60–0.72). Agreement between self-reported COPD and EMR-based COPD was (ĸ = 0.52 (0.42–0.62)). Self-report = self-reported data based on the ECRHSIII screenings questionnaire, EMR = Electronic Medical Records, COPD-LLN = COPD LLN-definition based on post-bronchodilator measurement, COPD-GOLD = COPD GOLD-definition based on post-bronchodilator measurement. The reference value was based on spirometry (LLN and GOLD). The different definitions for COPD are presented in Table 2.