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. 2017 Feb 24;13(2):e1006232. doi: 10.1371/journal.ppat.1006232

Fig 8. HCV vsRNA sequence polymorphisms correlated with PTPRE inhibition in vivo.

Fig 8

HCV E2 RNA was amplified from plasma obtained from ten HCV-infected subjects and the vsRNA region was sequenced (A). The putative “seed” sequence for PTPRE is underlined. PTPRE expression levels correlated with the percent complementarity between the HCV vsRNA and the two PTPRE 3’UTR target site sequences (Spearman correlation used to calculate R and P values, and results of best-fit linear regression analysis are shown). Ref = reference sequence from infectious HCV clone.