Table 1. Target prognostic analysis for the PLIN1 expression level in 18 pools corresponding to combinations of populations (ER and nodal status) and event criteria (MR or AE).

Nodal status	Estrogen receptor status	Event status	p value	HR	95% CI	No. patients	No. events
NM	ER+	AE	< 0.0001	0.87	0.81–0.92	3,600	11
NM	ER+	MR	< 0.0001	0.84	0.77–0.90	2,757	658
N−	ER+	MR	0.0001	0.79	0.70–0.89	1,389	312
NM	ERM	MR	0.0003	0.89	0.84–0.95	3,826	993
NM	ERM	AE	0.0006	0.92	0.87–0.96	5,041	1,636
N−	ER+	AE	0.0009	0.85	0.77–0.93	1,744	492
N−	ERM	MR	0.006	0.88	0.80–0.96	1,887	454
N−	ERM	AE	0.01	0.91	0.84–0.98	2,404	711
N+	ER+	AE	0.02	0.89	0.80–0.98	1,023	389
N+	ER+	MR	0.03	0.86	0.75–0.98	677	202
N+	ERM	MR	0.04	0.89	0.79–0.99	980	322
N+	ERM	AE	0.06	0.93	0.86–1.00	1,470	60
NM	ER−	AE	0.08	1.08	0.99–1.17	1,400	525
NM	ER−	MR	0.14	1.08	0.98–1.20	1,039	330
N−	ER−	MR	0.14	1.13	0.96–1.33	479	140
N−	ER−	AE	0.27	1.08	0.94–1.23	635	2
N+	ER−	AE	0.56	1.04	0.91–1.19	438	212
N+	ER−	MR	0.73	1.03	0.86–1.25	295	119

N (+,−, m): nodal status (+: positive, −: negative, m: mixed); estrogen receptor status (+: positive, −: negative, m: mixed); HR: hazard ratio (values are rounded to 2 decimal places); 95% CI: 95% confidence interval (values were rounded to 2 decimal places); ER (+,−, m).