Figure 1. DNA copy number changes for tumor-B (blue) and -K (red).

(A) Genome-wide DNA copy number plot. (B) Landscape view of chromosome 12 with high-level amplification for CDK4, MDM2, FRS2 and KITLG. (C) Detailed view on the flanking genomic region for all four genes; red dots indicate data points from either tumor with a log₂ ratio > 0 and green dots with log₂ ratio < 0. The ratio is plotted according to position with triangular smoothing of 200 kb, with blue line indicating tumor B, red tumor K.